Contraction and relaxation of smooth muscle and cyclic nucleotides
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چکیده
منابع مشابه
Regulation of contraction and relaxation in arterial smooth muscle.
Intracellular calcium concentration ([Ca2+]i)-dependent activation of myosin light chain kinase and its phosphorylation of the 20-kd light chain of myosin is generally considered the primary mechanism responsible for regulation of contractile force in arterial smooth muscle. However, recent data suggest that the relation between [Ca2+]i and myosin light chain phosphorylation is variable and dep...
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To elucidate the mechanism of cyclic nucleotides, such as adenosine 3',5'-cyclic monophosphate (cAMP) and guanosine 3',5' -cyclic monophosphate (cGMP), in the regulation of human gastric motility, we examined the effects of forskolin (FSK), isoproterenol (ISO) and sodium nitroprusside (SNP) on the spontaneous, high K(+) and acetylcholine (ACh)-induced contractions of corporal circular smooth mu...
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We examined the effects of cyclic AMP (cAMP) on the intracellular Ca2+ release in both the intact and skinned arterial smooth muscle. The amount of Ca2+ in the sarcoplasmic reticulum (SR) was estimated indirectly by caffeine-induced contraction of the skinned preparation and directly by caffeine-stimulated 45Ca efflux from the previously labeled skinned preparation. The norepinephrine-induced r...
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Marston, S. B. & Smith, C. W. J. (1984)J. Muscle Res. 5,559-575 Marston. S. B. & Smith, C. W. J. (1 985) J. Muscle Res. 6,669-708 Marston, S. B., Lehman, W., Moody. C. & Pritchard, K. ( 1 988) in Calcium and Calcium binding Proteins (Gerday, C., Gilles, R. & Bolis, L., eds.). pp. 69-8 1, Springer Verlag, Heidelberg Mathew, J. K., Krolak, J. M. & Dedman, J. R. ( 1 986) J. Cell. Biochem. 32,223-2...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1976
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)65890-7